The Adventure of the Cardboard Box


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Come mid-morning, Holmes and Watson find themselves with three gifts, two cases, and one mild hangover. If they're lucky, they won't be additionally burdened with a partridge in a pear tree—though with the direction everything is heading, Watson wouldn't bet against it. I did nothing. I could determine neither who her killer was, nor where he had gone. Why I should have been so richly rewarded for such an abysmal failure, I will never truly understand.

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I have always felt vaguely uncomfortable with the canonical description of how Sherlock got his violin, so I have updated it to BBCverse and played around with it a bit. Here is my story of that pawnbroker, and how Sherlock acquired his Stradivarius. Finding a Strad in a pawnshop, and being able to buy it for dirt cheap This story has been written for an italian fanfiction contest and had to fulfill some requests: Body parts have been sent to the Europe's leaders; John has to solve the case alone; include an empty flat and 'Floris eaux de parfum Sirena'.

Although as good scientists we may want more data, this would have required exposing more eligible patients to best medical therapy. Although there may be societal benefit to increasing the precision of our estimate of the treatment effect, I do not think that is right to place the burden of this discovery on our patients I am not certain even of this premise- I do believe that estimates of the NNT for PCI for STEMI are considerably higher — e. Based on our best available estimates from all five trials NNT range , this would have resulted in avoidable disability in between patients.

Plot Summary of the Adventure of the Cardboard Box

I do not myself think this is justifiable. We are the EMCrit Project , a team of independent medical bloggers and podcasters joined together by our common love of cutting-edge care, iconoclastic ramblings, and FOAM. About EMNerd Chronicles.


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A randomized trial of intraarterial treatment for acute ischemic stroke. N Engl J Med. Problems of stopping trials early. Practical problems in interim analyses, with particular regard to estimation. Control Clin Trials ;10 suppl 4 S.

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Stopping randomized trials early for benefit and estimation of treatment effects: systematic review and meta-regression analysis. Endovascular therapy after intravenous t-PA versus t-PA alone for stroke. Endovascular treatment for acute ischemic stroke. A trial of imaging selection and endovascular treatment for ischemic stroke. About Latest Posts.

Arthur Conan Doyle

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Your Job i. Most reacted comment. Hottest comment thread. Recent comment authors. Stephen van Gaal. Thank you for your support and feedback! Interventional therapy for stroke: the evidence - First10EM. Like Us on Facebook. Subscribe by Email. Miss Susan Cushing of Croydon receives a parcel in the post that contains two severed human ears packed in coarse salt.

Inspector Lestrade of Scotland Yard suspects a prank by three medical students whom Miss Cushing was forced to evict because of their unruly behaviour. The parcel was sent from Belfast, the city of origin of one of the former boarders. Upon examining the parcel himself, Holmes is convinced that it is evidence of a serious crime. He reasons that a medical student with access to a dissection laboratory would likely use something other than plain salt to preserve human remains, and would be able to make a more precise cut than the roughly hacked ears suggest.

The address on the package, roughly written and with a spelling correction, suggests to Holmes that the sender lacks education and is unfamiliar with Croydon. The knot in the string suggests to Holmes that they are looking for someone with sailing experience.

The Adventure of the Cardboard Box by Arthur Conan Doyle - FictionDB

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